N-[(R)-(6-Bromo-2-methoxyquinolin-3-yl)(phenyl)methyl]-N-[(S)-1-(4-methoxyphenyl)ethyl]-2-(piperazin-1-yl)acetamide
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چکیده
منابع مشابه
N-[(R)-(6-Bromo-2-methoxyquinolin-3-yl)(phenyl)methyl]-N-[(S)-1-(4-methoxyphenyl)ethyl]-2-(piperazin-1-yl)acetamide
In the title compound, C(32)H(35)BrN(4)O(3), the piperazine ring exists in a chair conformation. The quinoline ring system is oriented at dihedral angles of 82.70 (17) and 19.54 (17)° to the phenyl and meth-oxy-phenyl rings, respectively. Weak inter-molecular C-H⋯π inter-actions are present in the crystal structure.
متن کاملN-{2-[4-(2-Hydroxyethyl)piperazin-1-yl]ethyl}phthalimide
In the title compound, C(16)H(21)N(3)O(3), the piperazine ring adopts a chair conformation, with its N-C bonds in pseudo-equatorial orientations. In the crystal, mol-ecules are linked by O-H⋯N hydrogen bonds, generating C(5) chains propagating in [101]. Weak aromatic π-π stacking inter-actions also occur [centroid-centroid separation = 3.899 (1) Å].
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N, N΄-3, 4-di(methylamino)-1, 2, 5-oxadiazole (1f) was prepared by dehydration of N, N΄-3, 4-di(methylamino)glyoxime (2f) in aqueous potassium hydroxid at 170-180 ˚C. Under similar conditions N, N΄-3, 4-di(benzylamino)-1, 2, 5-oxadiazole (1c) and N, N΄-3, 4-di(isopropylamino)...
متن کاملN-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}-4-nitro-N-(2-pyridyl)benzamide
In the title compound, C(25)H(27)N(5)O(4), the piperizine ring adopts a chair conformation. The dihedral angles between the pyridine ring and the two benzene rings are 65.5 (4) and 70.7 (4)°, while the dihedral angle between the two benzene rings is 17.3 (3)°. An intra-molecular C-H⋯O hydrogen bond occurs.
متن کاملN-[(6-Bromo-2-methoxy-3-quinolyl)phenylmethyl]-2-morpholino-N-(1-phenylethyl)acetamide
In the title compound, C(31)H(32)BrN(3)O(3), the morpholine ring adopts a chair conformation, and the planar quinoline system is twisted with respect to the phenyl rings, with dihedral angles of 17.6 (4) and 75.1 (3)°. Intramolecular C-H⋯O and C-H⋯N hydrogen bonds are present. The crystal packing is stabilized by weak C-H⋯O hydrogen bonding and C-H⋯π interactions.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2011
ISSN: 1600-5368
DOI: 10.1107/s1600536811040955